 |
|
|
|
 |
Trijani Suwandi, drg, Sp. Perio
• Dentist, graduated from Faculty of Dentistry, Trisakti University, year 1993
• Graduated in Periodontics, Faculty of Dentistry, University of Indonesia, year 2003
• Lecturer in Periodontology Department, Faculty of Dentistry, Trisakti University, Jakarta, Indonesia
• Practice :
- Clinical Specialist in Periodontology, Dental Hospital Trisakti University, Jakarta, Indonesia.
Telp (+62 21) 5672731 ext. 1709
- Citra Garden 1 ext. AD-2 no.15 West Jakarta. Telp (+62 21) 5403753
|
|
CLINICAL EFFECTS OF THE SUB GINGIVAL APPLICATION BETWEEN 25% METRONIDAZOLE GEL
AND 10% POVIDINE-IODINE AS ADJUNCTIVE THERAPY OF SCALING
AND ROOT PLANING IN CHRONIC PERIODONTITIS |
| Trijani Suwandi |
| Participant of Educational Program for Periodontic Specialist |
| Trijani Suwandi : Clinical effects of the subgingival application between 25% metronidazole gel and 10% povidine-iodine as adjunctive therapy of Scaling Root Planing (SRP) in Chronic Periodontitis. Journal of Dentistry University of Indonesia, 2003:10 (Special Edition), 669-674. |
|
|
|
|
Scaling and root planing may not result maximally due to teeth anatomy’s complexity which makes it difficult for the instruments to reach periodontal pocket so it will limit the root planing effectivity.1,2,3,4 Bacterial repopulation in tubules dentin and soft tissues closed to the pocket in the area that cannot be taken in the process of root planing may cause some disease.4
Because of the fact, the researcher would like to develop the use of anti microbial to take care of Chronic Periodontitis which can be given systemically and locally, either as single or adjunctive therapy towards mechanical therapy.1,2,3,5 The local application of anti microbial into the periodontal pocket has more advatages than systemic application.5 In systemic application, it needs high dose to reach the target area therefore it may cause side effects, such as sensitivity, problem of digestion, and resistance. The local application can reduce bacterial resistance toward non oral and minimize the side effects.4
These local anti microbial can be given in the form of gel, like metronidazole or solution, like PVP-1. Metronidazole concentration which is very common in the market is 25% and it is applied with paroject1. However, the use of metronidazole in the market is so small that it can be said it is not broad enough. This may be due to the fact that it is relatively difficult to obtain, expensive and inefficient. Therefore, the researcher came up with the idea to develop the mixture of 25% metronidazole gel.
Former research to see clinical effects was done by comparing the mixture of 15% with 25% metronidazole gel, as adjunctive therapy in scaling and root planing into 4-6mm pocket. In the 3rd week, the research showed that the mixture of 25% metronidazole gave clinical effects like decreasing of the pocket’s depth, increasing attachment more significantly that the mixture of 15% metronidazole gel. Whereas, the side effect of less bleeding between these two was not so significant.
The use of solution like 10% PVP-1, which is cheap enough, can be obtained and proved to be effective in increasing clinical effects. This solution can kill bacteria only in 5 minutes.6
Based on the above description, further research needs to be done to evaluate the clinical effects of the 25% metronidazole gel mixture as adjunctive therapy. This research is also meant to compare the application of 10% PVP-1 into pocket of  6mm in chronic Periodontitis in order to find cheaper mixture is which easier to obtain, easy to apply and effectively useful to reduce the flap surgery. |
|
|
|
|
|
|
|
